io.github.open-mtor-atlas/mtor-atlas

Oliver's mTOR Atlas

Evidence-labelled mTOR research: studies, entities, pathway claims, contradictions, open questions.

1.2.2
Version
remote + npm
Transport
11
Tools

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Tools (11)

  • atlas_about

    Dataset version, corpus snapshot date, counts, evidence-code legend and how to cite the dataset.

  • search_studies

    Search the curated studies by keywords (title, finding, authors, journal, model system), optionally filtered by evidence code, a linked entity (gene, drug, disease...) and year range. Returns summary records with evidence codes and URLs.

  • get_study

    Full record for one study by Atlas ID (e.g. "SAB1994"): abstract excerpt, extracted findings, linked entities, the relations it supports or contradicts, related open questions.

  • search_entities

    Find genes/proteins, complexes, drugs, diseases, processes, nutrients and outcomes by name or synonym.

  • get_entity

    One entity (gene/protein, complex, drug, disease, process...) with its linked studies as short cards (first studies_limit) and every pathway relation it takes part in as a one-line claim. Accepts an id, a name or a synonym.

  • find_relations

    Signed, evidence-linked pathway relations (claims such as "Rheb activates mTORC1"). Filter by an entity on either end, by source/target, effect, contested status or minimum strength of the best supporting evidence.

  • get_relation

    One pathway relation by ID (e.g. "RHEB-MTORC1"): mechanism, boundary conditions, confidence, supporting and conflicting studies.

  • evidence_between

    Direct curated relations between two entities (either direction) with full cards for the supporting and conflicting studies. Answers questions such as "what is the evidence that A acts on B?".

  • find_contradictions

    Relations the Atlas marks as contested or that carry conflicting studies, with both sides of the evidence. Optionally limited to one entity.

  • list_questions

    The Atlas's open questions (evidence gaps with testable hypotheses) and frontier questions.

  • get_question

    One open or frontier question by ID (e.g. "H1", "F2"): the gap, what changed, what is still open, how it could be tested, linked studies.